Standard of Care

From Standard of Care

T1-clinically inapparent, non palpable or visible by imaging

T1a-incidental histologic finding, ≤5% of resected tissue

T1b-incidental finding, >5% of resected tissue

T1c-tumor identified by needle biopsy, or any PSA elevation

T2-palpable or visible tumor, confined within the prostate

T2a-tumor involvement ≤1/2 of one lobe

T2b-tumor involvement of one lobe

T2c-tumor involvement of both lobes

T3-tumor extends through the capsule

T3a-tumor with extracapsular extension unilaterally or bilaterally

T3b-tumor involvement of the seminal vesicle

T4-tumor is fixed or invades adjacent structures

T4a-tumor invades bladder neck, external sphincter or rectum

T4b-tumor invades levator muscles or fixed to pelvic sidewalls

N0-no cancer cell in lymph nodes

N1-one positive lymph node smaller than 2 cm

N2-more than one positive node, or one that is 2-5 cm

N3 any positive node > than 5 cm

M0-no cancer spread outside the pelvis

M1-cancer spread outside the pelvis

Stage I-T1N0M0, Gleason score 6 or less, PSA less than 10 or T2a, N0 M0, Gleason score 6 or less, PSA less than 10.

Stage IIa- T1N0M0, Gleason score of 7, PSA less than 20 or T1, N0, M0, Gleason score of 6 or less, PSA at least 10 but less than 20, or T2a or T2b, N0 M0, Gleason score of 7 or less, PSA less than 20

Stage IIb-T2c, N0M0, any Gleason score, any PSA or T1 or T2, N0 M0, any Gleason score, PSA of 20 or more, T1 or T2, N0 M0, Gleason score of 8 or higher, any PSA

Stage III-T3, N0, M0, any Gleason score, any PSA

Stage IV-T4, N0, M0, any Gleason score, any PSA, or any T, N1, M0, any Gleason score, any PSA or any T, any N, M1, any Gleason score, any PSA