Obsessive-compulsive disorder
From Standard of Care
Refers to intrusive, anxiety, repetitive, ritualized behaviors.
A chronic psychiatric process with familial, social and work complications.
Affects up to 1 in 50 people.
Treatment consists of serotonin-reuptake inhibitors and cognitive behavioral therapy.
Present treatment leaves 25-40% of patients with persistent symptoms and functional limitations.
A double-blind cross over study of stimulation of the subthalamic nucleus decreased symptoms in patients with severe refractory obsessive compulsive disorder (Mallet).
Subthalamic stimulation does not effect measures of depression, anxiety, neuropsychological processes or self-assessment of disability.
Associated with significant dysfunction and psychiatric comorbidity.
Cognitive behavior therapy involves exposure and response prevention.
