Mast cells
From Standard of Care
Effector cells in allergic disorders and immunoglobin E immune responses.
Activated cells secrete inflammatory mediators in response to pathogens.
Tissue cells found close to blood vessels and are numerous at sites in close proximity to the external environment such as the skin and respiratory airways.
Recognize and respond to pathogens.
Relatively resistant to ultraviolet an gamma radiation.
Following activation produce histamine, cytokines, chemokines, and lipid mediators.
Can activate and recruit eosinophils, neutrophils and monocytes.
Have a role in immune response to bacterial infections.
Express Toll-like receptor 3 which recognizes viral double stranded RNA.
Can produce interferons via Toll-like receptor 2.
Can be infected by HIV, dengue virus and respiratory syncytial virus and can respond to such infections.
